干预前、后手术患者预防应用抗菌药物情况分析

Analysis of Prophylactic Utilization of Antimicrobial Agents during Perioperative Period before and after Intervention

目的:了解干预前、后手术患者预防应用抗菌药物的情况,促进临床合理用药。方法:选取泉州市第一医院(以下简称"我院")干预前(2013年)和干预后(2014年)的手术病例各200例,分析干预前、后抗菌药物的应用情况。结果:干预后,手术病例抗菌药物使用率由46.50%降至33.00%;抗菌药物应用种类明显减少,头孢唑林钠的使用率由21.51%提高至51.52%,头孢硫脒由10.75%降为0;抗菌药物给药时间与疗程的合理率由34.41%提高至51.51%。结论:干预后,我院抗菌药物应用更加合理,但仍有不合理之处,应继续加强干预管理。

OBJECTIVE： To investigate the prophylactic utilization of antimicrobial agents during perioperative period before and after intervention,and to promote rational drug use. METHODS： 200 cases of surgery patients before intervention（ 2013） and another 200 cases after intervention（ 2014） admitted to the First Hospital of Quanzhou（ hereinafter referred to as＂our hospital＂） were investigated,and the utilization situation of antimicrobial agents before and after intervention were analyzed. RESULTS： After intervention,the rate of antimicrobial agents use in surgery patients decreased from 46. 50% to33. 00%; the varieties of the antimicrobial agents use were obviously reduced,and the rate of cefazolin use increased from21. 51% to 51. 52% while the constituent ratio of cefathiamidine use decreased from 10. 75% to 0; the rational rate of drug use time and treatment course increased from 34. 41% to 51. 51%. CONCLUSIONS： After intervention,the utilization of antimicrobial agents has been more rational than before,but there are still some irrational problems. Thus,it is necessary to sequentially strengthen the management of intervention.