摘要
目的:通过了解郑州市第二人民医院(以下简称"我院")眼局部抗青光眼药用药情况,初步掌握本地区青光眼局部用药的临床应用特点、药品分布情况以及发展趋势。方法:通过药品管理系统,统计2010—2014年眼局部抗青光眼药物使用数量、销售金额的情况,利用限定日剂量(defined daily dose,DDD)、用药频度(defined daily dose system,DDDs)、限定日费用(daily drug cost,DDC),综合讨论进行用药分析。结果:我院抗青光眼局部用药销售数量、金额整体呈逐年上升趋势,噻吗洛尔呈下降趋势,曲伏前列素、溴莫尼定上升幅度明显;噻吗洛尔、曲伏前列素DDDs变化明显,其他药物的DDDs排序无显著性变化。结论:噻吗洛尔在临床使用过程中逐渐被卡替洛尔所代替;布林佐胺在青光眼药物治疗中占重要位置;曲伏前列素的临床应用率逐年升高。
OBJECTIVE： To investigate the application of local anti-glaucoma drugs in the Second People＇s Hospital of Zhengzhou（ hereinafter referred to as ＂our hospital ＂）,and then get preliminary information about the clinical application characteristics,drugs distributions and the development tendency of local anti-glaucoma drugs. METHODS：Through drug management system,the consumption amount,consumption sum of anti-glaucoma drugs were statistically collected. And comprehensively analysis was conducted on the defined daily dose（ DDD）,defined daily dose system（ DDDs）,and daily drug cost（ DDC）. RESULTS： The sales amount,consumption sum of local anti-glaucoma drugs were in upward trend in our hospital,while timolol decreased,and travoprost and brimonidine both had a significant increase.DDDs of timolol and travoprost had changed significantly,and the others had no significant change. CONCLUSIONS：Timolol has been gradually replaced by carteolol in the process of clinical application; brinzolamide plays an important role in glaucoma medications; and the use rate of travoprost stepped up steadily yearly in clinical application.
出处
《中国医院用药评价与分析》
2015年第12期1629-1631,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
2014年度郑州市科技攻关项目(NO.141PPTGG340)
