172例药品不良反应报告分析

Analysis of 172 Cases of Adverse Drug Reaction Reports

目的:了解安徽省第二人民医院(以下简称"我院")药品不良反应(adverse drug reaction,ADR)发生的特点与规律,为减少ADR的发生提供参考。方法:采用回顾性调查方法,对我院2013年1月—2014年12月上报的172例ADR报告进行分析。结果:172例ADR中,男女患者分别为93、79例;≥60岁患者80例(占46.51%);静脉给药引发的ADR为160例(占93.02%);抗感染药引发的ADR为45例(26.16%);ADR的临床表现主要为皮肤及其附件损害,共56例(32.56%)。结论:临床应重视ADR的监测与上报工作,规范药品的合理使用,减少ADR的发生。

OBJECTIVE：To investigate the regulations and characteristics of the adverse drug reaction（ ADR） in the Second People＇s Hospital of Anhui Province （ hereinafter referred to as ＂our hospital＂） , and to provide reference for the reduction of the occurrence of ADR. METHODS：Retrospective investigation was adopted, a total of 172 cases of ADR reports collected in our hospital from Jan. 2013 to Dec. 2014 were statistically analyzed. RESULTS：Of the total 172 cases, 93 cases were male, 79 cases were female. There were 80 cases of senile patients aged above 60 years old, accounting for 46. 51%;there were 160 cases of ADR induced by intravenous dripping, accounting for 93. 02%;most ADR were induced by antibiotics drugs, accounting for 26. 16%; the most common clinical manifestations were the damage of skin and its appendants, totally with 56 cases, accounting for 32. 56%. CONCLUSIONS：The clinic should attach more importance to ADR monitoring and report, regulate the rational use of drugs so as to reduce the incidence of ADR.