25例胃黏膜高级别上皮内瘤变的临床病理分析

Clinical Pathological Analysis of 25 Cases With High Grade Gastric Mucosa Tumor

目的探讨胃黏膜高级别上皮内瘤变临床病理诊断在早期胃癌诊断中的意义。方法回顾性分析25例胃黏膜高级别上皮内瘤变患者术后病理结果。结果术前均诊断为高级别上皮内瘤变,术后病理证实腺癌18例;其中侵犯黏膜及黏膜下层的早期胃癌13例;侵犯肌层及浆膜层伴淋巴结转移的中晚期胃癌5例。结论对胃黏膜高级别上皮内瘤变的准确诊断和正确认识将有助于提高早期胃癌的检出率,并指导选择合理的治疗方法,提高胃癌患者的生存率。

Objective To explore valuation of gastric mucous high-grade intraepithelial neoplasia pathological diagnosis significance in the early diagnosis of gastric cancer. Methods 25 patients with gastric mucous highgrade intraepithelial neoplasia were analyzed retrospectively. Results Preoperative, all were diagnosed high-grade intraepithelial neoplasia, postoperative, 18 cases were confirmed adenocarcinoma by pathology diagnosis, including 13 cases with early gastric cancer of violated mucous membrane and submucosa and 5 cases middle-late gastric cancer of infringement muscularis and serosa with lymph node metastasis. Conclusion Accurate diagnosis of gastric mucous high-grade intraepithelial neoplasia will improve the early gastric cancer detection rate, and guiding reasonable therapeutic method, which will improve the survival rate of patients with gastric cancer.