摘要
目的探讨HBsAg阳性母亲其婴幼儿联合阻断后无/低应答状态及加强免疫效果。方法收集2014年1~12月出生,接受计划免疫的婴儿,在婴儿接种后12个月根据应答情况分为无应答组和低应答组。对两组婴儿进行加强接种乙肝疫苗10μg/次,1月后复查应答状态。对比无应答组和低应答组（加强接种乙肝疫苗前后）HBsAb水平。结果加强接种乙肝疫苗前、后无应答组和低应答组HBsAb水平结果比较差异有统计学意义（P〈0.05）;无应答组和低应答组在加强接种乙肝疫苗前后HBsAb水平组内比较差异有统计学意义（P〈0.05）。结论本次研究认为HBsAg阳性母亲其婴幼儿联合阻断后仍有无/低应答状态的发生,在加强免疫后,HBs Ab水平能够明显提高。
Objective To evaluate the role of HBs Ag positive mothers non/low response after the infant joint block status and enhance the immune effect. Methods From January to December 2014 was born, accept infant immunization, 12 months after infant vaccination according to the response is divided into no answer and low response group. To strengthen the hepatitis b vaccination two groups of babies 10μg/time, after 1 month review state. Compared to no answer and low response group（strengthen） before and after hepatitis b vaccination HBs Ab level. Results Strengthen the hepatitis b vaccination before and after no response and low response group HBs Ab level results compare the difference was statistically significant（P〈0.05）. No answer and low response group to strengthen hepatitis b vaccination HBs Ab level within the group comparison before and after the difference was statistically significant（P〈0.05）. Conclusion This study thinks that HBs Ag positive mother still have after the infant joint block/low response state, after strengthening immune, HBs Ab level can significantly improve.
出处
《中国继续医学教育》
2015年第33期115-116,共2页
China Continuing Medical Education
