肺癌患者睡眠障碍对生存质量的影响

Effect of sleep disturbance on quality of life in lung cancer patients

目的探讨肺癌患者睡眠障碍对生存质量的影响。方法采用阿森斯失眠自评量表(AIS)及欧洲癌症研究与治疗组织生存质量核心问卷(EORTC QLQ-C30)对我院收治的110例肺癌患者进行调查。根据AIS评分将肺癌患者分为睡眠障碍组(51例)和睡眠无障碍组(59例),分析睡眠障碍对生存质量的影响。结果肺癌患者AIS总分(7.56±3.23)分,51例(46.4%)患者存在睡眠障碍(AIS总≥6分)。肺癌患者整体健康状况得分(58.61±16.34)分,属于较差范畴。与睡眠无障碍组相比,睡眠障碍组生存质量功能领域(除社会功能)和整体健康状况得分较低,症状领域和单测项目(除经济困难、腹泻、便秘)得分较高,差异具有统计学意义(P<0.05)。结论肺癌患者的睡眠障碍发生率较高,睡眠障碍会导致肺癌患者生存质量下降。

Objective To explore the effect of sleep disturbanee on quality of life. Methods Totally 110 lung cancer patients who were treated in our hospital were investigated with the Athens Sleep Insomnia Scales（AIS） and European Organization for Research and Treatment of Cancer,Quality Life Questionnaire C30 （ EORTC QLQ-C30）. According to AIS scores,lung cancer patients were di- vided into sleep disturbance group and non-sleep disturbance group, to explore the effect of sleep disturbance on quality of life. Results The total score of AIS was 7.54 ± 3.23,51 cases （46.4%） of lung cancer patients had sleep disturbance （ AIS ≥ 6）. The total score of global health status was 58.61 ±16.34 with in the poorer ranger. Compared with the non-sleep disturbance group ,the patients with sleep disturbance had lower disturbance and had lower score in functional domains （excepting for social functioning） and global health status, but higher score in symptom domains （ excepting for financial difficulty, constipation and diarrhea） （P 〈 0. 05 ）. Conclusion The prevalence of the sleep disturbance is high and the quality of life is poor in lung cancer patients. Sleep disturbance can reduce quality of life in lung cancer patients.