30岁以上中国人眼角膜Q值及相关因素分析

Corneal Q value and its ralated factors in Chinese older than 30 years

目的分析30岁以上中国人眼角膜Q值及其影响因素。设计横断面研究。研究对象以邯郸眼病研究的检测对象为目标人群，按照自愿原则采集角膜地形图，测量1683人的右眼，其中男性728人，女性955人，平均年龄（53．64±11．0）岁（30～107岁）。方法使用OrbscanⅡ采集角膜地形图，分析角膜在3．0min、5．0min和7．0min测量孔径下的前后表面Q值及其与年龄、性别、屈光度的关系。主要指标角膜前、后表面Q值。结果角膜前表面Q值在3．0min、5．0min和7．0min测量孔径下平均值分别为-0．28±0．175、-0．28＋0．175和-0．29±0．175；角膜后表面Q值在3．0mm、5．0mm和7．0min孔径下平均值分别为-0．26±0．216、-0．26＋0．214和-0．26±0．215。在5mm孔径下角膜前表面Q值与年龄、屈光度负相关（B=-0．003和-0．013，P〈0．01和-0．016）；角膜后表面Q值与年龄、屈光度正相关（B=0．002和0．016，P=0．036和=0．043）。结论中国人眼角膜Q值与欧美人存在差异，且受年龄、屈光度的影响。

Objective To describe the corneal Q value in Chinese older than 30 and to evaluate the associated factors. Design Cross-sectional study. Participants 1683 participants from the Handan Eye Study whose right eyes accepted the corneal topography, of which 955 were female and 728 were male. The average age was （53.6±11.0） years 00 ~ 107 years）. Methods The corneal Q values of anterior surface and posterior surface were measured at the 3 ram, 5 nun and 7 mm diameter annulus by Orbsean corneal topography. The association of the corneal Q values with age, gender, and dioptre was analyzed. Main Outcome Measures The corneal Q value of anterior and posterior surface. Results The average corneal Q value of anterior surface at 3 mm, 5 mm and 7 mm diameter annulus was -0.28±0.175, -0.28±0.175, and -0.29±0.175 respectively and the values at 5 mm diameter annulus were negatively associated with age （B=-0.003, P〈0.01） and dioptre （B=-0.013, P=0.016）. The average Q value of posterior surface at 3 mm, 5 mm and 7 mm diameter an- nulus was -0.26±0.216, -0.26±0.214, and -0.26±0.215, respectively and the values at 5 nun diameter annulus were positively associat- ed with age （B=0.002, P=0.036） and dioptre （B=0.016, P=0.043）. Conclusion The corneal Q value in Chinese was different from that of Europeans and affected by age and dioptre.