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成人阻塞性睡眠呼吸暂停低通气综合征 被引量:1

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摘要 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)是一种由于睡眠中上呼吸道反复塌陷而导致血氧饱和度下降和睡眠结构紊乱的疾病.其主要临床表现为夜间睡眠打鼾、呼吸暂停和白天嗜睡.OSAHS发病机制多种多样,可能的机制有上呼吸道狭窄、呼吸调控不稳定、觉醒阈值低、肺容量小和上呼吸道扩张肌功能紊乱等.肥胖、男性、年龄、更年期、液体潴留、腺样体和扁桃体肥大以及吸烟等因素是OSAHS的高危因素.60%~70%的OSAHS患者可耐受持续气道正压通气治疗并获得相对理想的效果,其他治疗方式还有口腔矫正、外科手术和减肥等.本文就OSAHS的发病机制、与其他疾病的相关性及治疗的研究进展做一综述.
出处 《国际耳鼻咽喉头颈外科杂志》 2015年第5期255-259,共5页 International Journal of Otolaryngology-Head and Neck Surgery
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参考文献39

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