宫颈癌调强放射治疗患者治疗依从性研究

Study on treatment compliance during intensity-modulated radiotherapy for cervical cancer

目的：研究宫颈癌调强放射治疗中患者对于治疗的依从性。方法：入组149例进行调强放射治疗的宫颈癌患者。统计治疗的计划次数,及实际的治疗持续的总天数。对于调强放射治疗中的进行的化疗及内照射次数也同样进行了统计。分析治疗延长与患者剂量的关系。结果：较多病人实际的治疗天数与计划天数差异,治疗中间终止的有6.04%,完全按照计划完成治疗的占17.45%,其余为有拉长治疗的时间。不计后装和化疗的天数时,患者的完全按照治疗进行的占25.5%,治疗延长1~4d,5~10d,大于10d的占35.57%,18.79%,7.38%。结论：宫颈癌调强放射治疗中治疗的依从性较差,对于延长治疗总时间过长（〉5d）的患者应给适当的剂量加量,以便达到预期的治疗效果。

Objective： To study on treatment compliance during intensity - modulated radiotherapy for cervical cancer. Methods： 149 patients were enrolled for IMRT for cervical cancer. We counted total fractions, total days during treatment, fractions of brachythe- rapy and total times of chemotherapy. Then we analyzed the relation between the total days delay and the total dose. Results： Most of patients delayed treatment total days in. 6.04% patients stopped treatment. 17.45% patients accorded the planning. Others had de- layed treatment days. Excluding brachytherapy days and chemotherapy days, the delayed days of 1 to 4, 5 to 10 and more than 10 days were 35.57%, 18. 79%, 7. 38%. Conclusion： The treatment compliance is lower during intensity - modulated radiotherapy for cervi- cal cancer. If you want get good radiotherapy for treatment delayed more than 5 days, you should add total dose fraction.