单中心腹膜透析相关性细菌性与真菌性腹膜炎的临床对比分析

Clinical comparative analysis of monocentric peritoneal dialysis-related bacterial and fungal peritonitis

目的对比单中心腹膜透析相关性细菌性与真菌性腹膜炎的临床特点,以期达到更好地预防及治疗。方法回顾性分析330例腹膜透析患者中发生相关性腹膜炎患者的临床资料。结果细菌性腹膜炎组患者退出率20.7%,死亡率15.7%。晚期拔管的死亡率风险比2.6。真菌性腹膜炎组退出率100.0%,死亡率30.0%;3例死亡的患者拔管后均未进行规律抗真菌治疗。结论在细菌性腹膜炎中,早期拔管可改善患者的预后。腹膜透析相关性真菌性腹膜炎临床预后差,提示拔管后进行规律抗真菌治疗可改善患者的预后。

Objective To compare clinical characteristics of monocentric peritoneal dialysis-related bacterial and fungal peritonitis, in order to achieve better prevention and treatment.Methods Clinical data of 330 patients with peritoneal dialysis-related peritonitis were retrospectively analyzed.Results The exit rate and mortality rate in bacterial peritonitis group were 20.7% and 15.7%. The death risk of late extubation was 2.6. Fungal peritonitis group had exit rate and mortality rate as 100.0% and 30.0%. There were 3 death cases without regular antifungal therapy after extubation.Conclusion Early extubation can improve prognosis of bacterial peritonitis. Due to poor clinical prognosis of peritoneal dialysis-related fungal peritonitis, implement of regular antifungal therapy after extubation can improve patients＆#39; prognosis.