期刊文献+

左西孟旦与米力农对心力衰竭的治疗效果分析

下载PDF
导出
摘要 目的比较左西孟旦与米力农对心力衰竭的治疗效果。方法 86例心力衰竭患者,随机分为对照组和观察组,各43例。对照组以米力农治疗,观察组以左西孟旦治疗,分析比较两组疗效。结果观察组治疗总有效率为88.4%、不良反应发生率为9.3%,均优于对照组的69.8%、30.2%(P<0.05);治疗后左心室射血分数、每搏心输出量、6个月随访时心血管事件发生率及再住院率均显著优于对照组(P<0.05)。结论与米力农相比,左西孟旦对心力衰竭的治疗价值更为显著,值得临床推广。
作者 周长宇
机构地区 辽阳市中心医院
出处 《中国实用医药》 2015年第35期124-125,共2页 China Practical Medicine
  • 相关文献

参考文献3

二级参考文献24

  • 1Follath F,Cleland JG,Just H,et al.Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure(the LIDO study):a randomized double-blind trial[J].Lancet,2002,360(9328):196-202.
  • 2Moiseyev VS,Pōder P,Andrejevs N,et al.Safety and efficacy of a novel calcium sensitizer.Levosimendan,in patients with left ventricular failure due to an acute myocardial infarction.A randomized,placebo-controlled,double-blind study(RUSSLAN)[J].Eur Heart J,2002,23(18):1422-1432.
  • 3Cleland JG,Ghosh J,Freemantle N,et al.Clinical trials update and cumulative meta-analyses from the American College of Cardiology:WATCH,SCD-HeFT,DINAMIT,CASINO,INSPIRE,STRATUS-US,RIO-Lipids and cardiac resynchronisation therapy in heart failure[J].Eur J Heart Fall,2004,6(4):501-508.
  • 4Lehtonen L.Levosimendan:a calcium-sensitizing agent for the treatment of patients with decompensated heart failure[J].Curr Heart Fail Rep,2004,1(3):136-144.
  • 5Ishitani T,Hattori Y,Sakuraya F,et al.Effects of Ca2+sensitizers on contraction,[Ca2+]i transient and myofilament Ca2+sensitivity in diabetic rat myocardium:potential usefulness as inotropic agents[J].J Pharmacol Exp Ther,2001,298(2):613-622.
  • 6Dec GW.Acute decompensated heart failure:the shrinking role of inotropic therapy[J].Am Coil Cordial,2005,46(1):65-67.
  • 7Fosbol EL, Seibaek M, Brendorp B, et al. Danish investi- gation and arrhythmia on dofetilide (diamond) study group. Prognostic importance of changes in QRS duration over time associated with left ventricular dysfunction in pa- tients with congestive heart failure: the Diamond study [J]. J Card Fail, 2008, 14(3):850-853.
  • 8Moss AJ, Hail WJ, Cannom DS, et al. Cardiac-resyn- chronization therapy for the prevention of heart-failure events[J]. N EnglJ Med, 2009,361:1 329-1 338.
  • 9Tang AS, Wells GA, Talajic M, et al. Cardiac-resyn- chronization therapy for mild-to-moderate heart failure [J]. N EnglJ Med, 2010,363:2 385-2 395.
  • 10Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-re- synchronization therapy with or without an implantable defibrillator in advanced chronic heart failure[J]. N Engl J Med,2004,350:2 140-2 150.

共引文献66

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部