阿托伐他汀治疗慢性阻塞性肺疾病中的疗效分析

Analysis of curative effect by atorvastatin in the treatment of chronic obstructive pulmonary disease

目的探讨阿托伐他汀在慢性阻塞性肺疾病中的治疗效果。方法 115例慢性阻塞性肺疾病患者,随机分为对照组57例和观察组58例。对照组给予常规治疗,观察组在对照组基础上采用阿托伐他汀治疗,1次/d,20 mg/次,于每晚口服。比较两组治疗效果。结果观察组患者治疗总有效率为94.83%,高于对照组患者的82.46%,两组比较差异有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论阿托伐他汀治疗慢性阻塞性肺疾病安全有效,具有临床推广价值。

Objective To investigate curative effect by atorvastatin in the treatment of chronic obstructive pulmonary disease. Methods A total of 115 patients with chronic obstructive pulmonary disease were randomly divided into control group with 57 cases and observation group with 58 cases. The control group received conventional treatment, and the observation group received additional atorvastatin for treatment once a day by 20 mg per time through oral administration every night. Curative effects of the two groups were compared. Results The observation group had higher total effective rate as 94.83% than 82.46% of the control group. Their difference had statistical significance （P〈0.05）. There was no statistically significant difference of incidence of adverse reactions between the two groups （P〉0.05）. Conclusion Atorvastatin is safe and effective in treating chronic obstrtictive pulmonary disease, and it contains value for clinical promotion.