老年患者实施丙泊酚联合依托咪酯的诱导作用

Effect of propofol combined with etomidate induction in elderly patients

目的探究老年患者实施丙泊酚联合依托咪酯的诱导作用。方法对2012年7月—2014年11月在本院接受麻醉治疗的50例老年患者的临床资料进行回顾性分析,并且根据麻醉诱导方式的不同,随机分为两组各25例,对照组(单纯丙泊酚诱导)和观察组(丙泊酚联合依托咪酯诱导),对比分析丙泊酚联合依托咪酯老年患者全麻诱导中对循环功能的影响。计量资料比较采用t检验,计数资料比较采用χ2检验,P<0.05为差异有统计学意义。结果观察组患者的手术时间、药量、苏醒时间、疼痛持续时间,分别为(85.74±13.58)、(0.24±0.07)、(28.95±4.73)、(32.53±10.56)min,均明显短于对照组[(146.37±11.85)、(0.58±0.11)、(58.49±6.71)、(73.34±9.85)min],差异均有统计学意义(均P<0.05)。两组患者术后循环功能情况评分[(11.32±3.08)、(17.84±4.52)分]、术前后循环功能评分上升幅度[(3.11±0.75)、(10.43±1.36)分]比较,差异均有统计学意义(均P<0.05)。对照组的总满意度为68.00%,观察组为92.00%,两组患者比较差异有统计学意义(P<0.05)。结论老年患者实施丙泊酚联合依托咪酯的麻醉诱导可有效提高患者的耐受力,缩短临床治疗时间,降低患者的疼痛,加快苏醒时间,改善循环功能。

Objective To explore the effect of propofol combined with etomidate induction in elderly patients. Methods The data of 50 eases of elderly patients with anesthesia were retrospectively analyzed from July 2012 to November 2014.According to anesthesia induction, all patients were randomly divided into two groups, control group（pure prepofol induced ）and observation group （propofol and etomidate induced）, 25 cases in each group, the influence of propofol combined with etomidate induction for circulatory function was analyzed. Measurement data was processed by t test, count data was used by chi square test,P〈0.05 was considered statistically significant.Results The operation time, dosage, recovery time and pain duration of observation group [（85.74 ± 13.58）,（0.24 ±0.07）,（28.95 ±4.73）,（32.53 ±10.56）min] were significantly shorter than those in the control group [（ 146.37 ± 11.85 ）,（0.58 ± 0.11 ）,（ 58.49 ± 6.71 ）,（ 73.34 ± 9.85 ）min]（aU P〈0.05）. In the two groups, the scores of postoperative circulatory function were （11.32 ± 3.08） and （4.52 ± 17.84）, and the ascensional range of scores of circulatory function were[（3.11 ± 0.75）,（10.43 ± 1.36）], the differences were statistically significant （all P〈0.05）. The total satisfaction of the control group was 68.00%, the observation group was 92.00%, the difference between the two groups was statistically significant（P〈0.05）. Conclusion Elderly patients with implementation of propofol and etomidate induction of anesthesia can effectively improve the patients＇ tolerance, shorten treatment time, reduce the patients＇ pain, accelerate the recovery time of patients, improve the patient＇s circulatory function.