右美托咪啶对高血压患者行腹腔镜胃癌手术血流动力学的影响

Effects of Dexmedetomidine on hemodynamic status during laparoscopy assisted gastric cancer surgery in patients with hypertension

目的:探讨右美托咪啶对高血压患者行腹腔镜胃癌手术血流动力学的影响。方法:选取60例行腹腔镜胃癌术治疗的高血压患者为研究对象,随机分为D组(右美托咪啶组)与C组(对照组)。观察两组在插管前(T1)、后(T2)及建立气腹时(T3)、拔管时(T4)、拔管后(T5)的心率(HR)、收缩压(SBP)等。结果:D组患者HR、SBP、舒张压(DBP)、心排量(CO)、每搏指数(SVI)、每搏变异度(SVV)、全身血管阻力指数(SVRI)等血流动力学观察指标在T2、T3、T4及T5时均优于C组患者,差异有统计学意义(P<0.05)。结论:高血压患者行腹腔镜胃癌术应用右美托咪啶进行辅助治疗,可以有效地改善患者血流动力学指标,有利于手术的顺利进行与术后康复。

Objective：To explore the effects of Dexmedetomidine on hemodynamic status during laparoscopy assisted gastric cancer surgery in patients with hypertension.Methods：60hypertension patients with laparoscopy assisted gastric cancer surgery were abstracted,and were randomly divided into group D（Dexmedetomidine group）and group C（control group）.The heart rate（HR）,systolic blood pressure（SBP）,etc at T1,T2,T3,T4,T5 were observed.Results：With comparison of time points（T2,T3,T4,T5）,the hemodynamic parameters of patients in the group D were better than those in the group C,including heart rate（HR）,systolic blood pressure（SBP）,diastolic blood pressure（DBP）,cardiac output（CO）,stroke volume index（SVI）,stroke volume variation（SVV）,systemic vascular resistance index（SVRI）,etc with the statistical significance（P〈0.05）.Conclusion：The application of Dexmedetomidine in hypertensive patients with laparoscopy assisted gastric cancer surgery can effectively improve the hemodynamic parameters of patients,more conducive to operation and postoperative rehabilitation.