亚麻醉剂量氯胺酮—芬太尼辅助小儿区域麻醉临床效果观察

The Clinical Effect for Anesthesia Dose of Ketamine and Fentanyl in the Treatment of Regional Anesthesia in Children

目的:观察亚麻醉剂量氯胺酮—芬太尼辅助小儿区域麻醉的临床效果。方法:90例手术患儿作为研究对象,按照数字分组法分为观察组和对照组,对照组单用氯胺酮椎管阻滞麻醉,观察组采用亚麻醉剂量氯胺酮—芬太尼辅助椎管阻滞麻醉。结果:两组均顺利完成手术,未发生手术或麻醉意外。观察组氯胺酮用量,氯胺酮人均追加次数,唤醒时间和不良反应率均显著小于对照组(P<0.05)。两组平均动脉压(MAP)比较,差异无统计学意义(P>0.05),观察组心率(HR)、脉搏氧饱和度(SpO_2)和呼吸频率(RR)等指标均显著低于对照组(P<0.01)。结论:采用亚麻醉剂量的氯胺酮—芬太尼辅助区域麻醉,可以在维持麻醉效果的基础上降低不良反应发生,缩短苏醒时间,对于促进患儿顺利康复有重要意义。

Objective To observe the clinical effect of the anesthetic dose of ketamine and fentanyl in the treatment of pediatric regional anesthesia. Methods 90 cases of surgical patients as the research object, according to the digital packet points as the observation group and the control group, the control group using a single ketamine spinal block anesthesia, the observation group with flax anesthetic dose of ketamine- fentanyl in spinal anesthesia anesthesia. Results（1） two groups were successfully completed the operation, no surgery or anesthesia accident.（2） in the observation group, the dosage of ketamine, the number of the number of ketamine, the wake-up time and the adverse reaction rate were significantly lower than those in the control group（P〈0.05）.（3） there was no significant difference between the two groups（P 0.05）, the MAP, SpO_2 and HR in the observation group were significantly lower than those in the control group（P 0.01）. Conclusion use of subanesthetic dose of ketamine- fentanyl assisted regional anesthesia, while maintaining the anesthetic effect of reducing adverse reaction and shorten the time of consciousness recovery, to promote patients recover successfully is of great significance. In surgery, to strengthen the management of anesthesia, to prevent respiratory depression.