IL-1β与糖尿病及糖尿病视网膜病变的相关研究进展

Research Progress of IL-1 with Diabetes Mellitus and Diabetic Retinopathy

糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病(diabetes mellitus,DM)最严重的并发症之一,具有很高的致盲率。DR发病机制复杂,至今未明。本文对白细胞介素IL-1β(Interleukin-1,IL-1β)在DR、DM中的作用和IL-1β对与DR发病过程中其他炎症因子的影响做一综述。

Diabetic retinopathy is one of the most severe diabetes complications with a high rate of blindness. The mechanism underlying the development of diabetic retinopathy is extremely complicated,and has not been elucidated yet. Here,we reviewed the role of interleukin-1β and the implication of the other inflammation factors during the progress of diabetes mellitus and diabetic retinopathy.