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Update on hepatitis C: Direct-acting antivirals 被引量:1

Update on hepatitis C: Direct-acting antivirals
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摘要 Hepatitis C virus(HCV) was discovered 26 years ago. For decades, interferon-based therapy has been the mainstay of treatment for HCV. Recently, several direct-acting antivirals(DAAs) have been approved for treatment of HCV-infected patients and to help combat the virus. These drugs have revolutionized the management of HCV as all-oral regimens with favorable side effect profiles and superior rates of sustained virological response. Emerging real-world data are demonstrating results comparable to registration trials for DAA agents. Suddenly, the potential for eradicating HCV is on the horizon. Hepatitis C virus(HCV) was discovered 26 years ago. For decades, interferon-based therapy has been the mainstay of treatment for HCV. Recently, several direct-acting antivirals(DAAs) have been approved for treatment of HCV-infected patients and to help combat the virus. These drugs have revolutionized the management of HCV as all-oral regimens with favorable side effect profiles and superior rates of sustained virological response. Emerging real-world data are demonstrating results comparable to registration trials for DAA agents. Suddenly, the potential for eradicating HCV is on the horizon.
出处 《World Journal of Hepatology》 CAS 2015年第28期2829-2833,共5页 世界肝病学杂志(英文版)(电子版)
关键词 HEPATITIS C virus Direct-acting ANTIVIRALS SUSTAINED VIROLOGIC response Management Treatment Hepatitis C virus Direct-acting antivirals Sustained virologic response Management Treatment
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