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水飞蓟素对黄曲霉毒素B_1致毒的红姑鱼幼鱼生长和毒素积累的影响 被引量:2

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摘要 本文研究了水飞蓟素(Silymarm,SM)对黄曲霉毒素B_1(AFB_1)致毒的红姑鱼幼鱼(6.5±0.5)g生长性能、血清和肝脏生化指标及AFB_1在肝脏和肌肉中残留的影响。试验共分为7组,对照组(A0组)饲喂基础饲粮,A100和A500组在基础饲料中分别添加100、500μg/kg AFB_1,A100-S1、A100-S2、A500-S1、A500-S2组分别在A100和A500组饲料中分别补充0.25、0.5 g/kg SM。试验进行12周。结果表明:AFB_1造成红姑鱼成活率显著下降,而补充SM后成活率显著提高(P〈0.05);各组红姑鱼形体指标及体组成无显著差异(P〈0.05);AFB_1导致血清SOD、GPT和GOT活性显著提高(P〈0.05),而肝脏T-AOC和SOD活性有明显提高,但仍显著低于A0组(P〈0.05)。结论,红姑鱼幼鱼摄食含AFB_1(100~500μg/kg)的饲料后,对其生长性能造成显著抑制,并引起肝脏抗氧化能力显著下降,引发肝损伤;补充SM使红姑鱼生长性能明显恢复,并可降低AFB_1在肝组织的残留。SM对红姑鱼幼鱼抗AFB_1的负面影响具有一定的缓解作用。
出处 《中国畜牧杂志》 CAS 北大核心 2016年第3期50-55,共6页 Chinese Journal of Animal Science
基金 国家科技支撑计划课题(2012BAD25B01-2) 中央高校基本科研业务费(XDJK2014C056)
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