摘要
越来越多的研究证据表明,孕妇妊娠期颗粒物暴露可通过母体影响胎儿的发育,导致早产、低出生体重、胎儿生长受限和潜在的不良心血管和呼吸道结局。但研究结果并不一致,且生物学机制尚不明确。本文通过对近年来国内外主要几种颗粒物人体暴露来源和其对早产影响及生物学机制作一简要综述,为控制空气污染和减少早产等不良妊娠结局的发生以及进一步探讨其可能的生物学机制提供基础依据。
More and more research evidences indicate that the exposure to particulate matter during pregnancy can impact the development of the fetus,resulting in preterm birth,lowbirth weight,growth restriction,and potentially adverse cardiovascular and respiratory outcomes. However,the results were inconsistent and the biological mechanism was not clear. This reviewsummarizes on harmful effects of several main particulate matter exposures on preterm birth and the sources of the exposures and provides references for controlling air pollution,reducing the occurrence of adverse pregnancy outcomes such as preterm delivery,and exploring possible biological mechanism of the effects.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2016年第2期239-243,共5页
Chinese Journal of Public Health
基金
国家自然科学基金(81330068
81373012)