摘要
研究表明肿瘤细胞发生上皮—间质转化(EMT)时所涉及的分子机制相当复杂,涉及到的信号通路在转录、翻译和翻译后水平均发挥调控作用。全文就EMT在恶性肿瘤中发生机制的研究进展作一综述。
Researches showed that there are complex molecular mechanism in epithelialmesenchymal transition(EMT) of tumor cells. These signaling pathways involved in EMT play regulation roles in the transcriptional,translational and post-translational levels. The recent progress in carcinogenesis mechanism of EMT in cancer was discussed in this paper.
出处
《中国肿瘤》
CAS
2016年第1期51-57,共7页
China Cancer
关键词
上皮—间质转化
恶性肿瘤
机制
epithelial-mesenchymal transition
cancer
mechanism