期刊文献+

Wells评分联合D-二聚体预测下肢深静脉血栓的价值 被引量:51

下载PDF
导出
摘要 目的:回顾分析Wells评分联合D-二聚体预测下肢深静脉血栓(DVT)形成的价值。方法:随机选取2013年1月至2015年1月入本院手外科、骨科治疗的骨折术后患者405例,根据多普勒超声结果将其分为DVT组(n=20)和非血栓组(n=385),另选同期接受体检的40例健康者作为对照组。对疑似DVT的53例患者分别以Wells评分、D-二聚体测定以及两者联合诊断骨折患者术后并发DVT的风险。结果:DVT组D-二聚体值明显高于非血栓组与健康对照组,差异有统计学意义(P<0.01):ROC曲线分析显示D-二聚体诊断骨折患者术后并发DVT的最佳临界值为0.575 mg/L,诊断敏感度为90%、特异度为64%,曲线下面积为0.840,P=0.000:根据Wells评分、D-二聚体以及两者联合对骨折合并DVT诊断的灵敏度分别为80.00%、90.00%、90.00%:特异度分别为75.76%、69.70%、87.88%:准确度分别为83.02%、77.36%、88.68%:阳性预测值分别为66.67%、64.29%、81.82%:阴性预测值分别为86.21%、92.00%、93.55%:阳性似然比分别为3.30、2.97、7.43:阴性似然比分别为0.26、0.14、0.11。结论:Wells评分联合血浆D-二聚体检测可以预测骨折患者术后并发下肢DVT的风险,为患者减少不必要的痛苦和检查费用。
出处 《实用医学杂志》 CAS 北大核心 2016年第1期98-101,共4页 The Journal of Practical Medicine
  • 相关文献

参考文献12

  • 1GREEN L , LAWRIE AS, PATEL R, et al. The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters [J] . Thromb Res, 2012, 130( 5) : 775-759.
  • 2BLANIE A, BELLAMY L, RHA YEM Y , et al. Duration of postoperative fibrinolysis after total hip or knee replacement: a laboratory follow-up study [J]. Thromb Res, 2013, 131 (1) : e6 -ell.
  • 3WELLS P. Overview and comparison of D-dimer assay kits for DVT and PE [J]. Clin Adv Hematol Oneol, 2004, 2 ( 3 ) : 160- 178.
  • 4WELLS PS. The role of qualitative D -dimer assays, clinical probability, and noninvasive tests for the diagnosis of Deep vein thrombosis and pulmonary embolism [J] . Semin Vasc Med, 2005,5(4):340-350.
  • 5UUNGQVIST M, SODERBERG M, MORITZ P, et al. Evaluation of Wells score and repeated D-dimer in diagnosing venous thromboembolism [J]. Eur J Intern Med, 2008, 19 ( 4 ) : 285-288.
  • 6GOODACRE S, SUTION AJ, SAMPSON FC. Meta-analysis: the value of clinical assessment in the diagnosis of deep venous thrombosis [J]. Ann Intern Med, 2005,143(2): 129-139.
  • 7LEE YK, CHOI YH, HA YC, et al. Does venous thromboembolism affect rehabilitation after hip fracture surgery [J]. Yonsei MedJ, 2013,54(4):1015-1019.
  • 8FISHER WD, AGNELLI G, GEORGE DJ , et al. Extended venous thromboembolism prophylaxis in patients undergoing hip fracture surgery-the SA VE- HIP3 study [J]. Bone Joint J, 2013, 95 ( 4) : 459-466.
  • 9VAN DER VELDE EF, TOLL DB, TEN CATE-HOEK AJ, et al. Comparing the diagnostic performance of 2 clinical decision rules to rule out deep vein thrombosis in primary care patients [J]. Ann Fam Med, 2011, 9( 1): 31-36.
  • 10TAMARIZ U, ENG J, SEGAL JB, et aI. Usefulness of clinical prediction rules for the diagnosis of venous thromboembolism: a systematic review [J]. Am J Med, 2004,117(9) :676-684.

二级参考文献27

共引文献87

同被引文献419

引证文献51

二级引证文献566

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部