上海市部分体检人群EB病毒血清学检测结果分析

Survey on Epstein Barr Virus VCA-IgA and EA-IgA Antibody Level Among Health Population in Shanghai

目的了解上海市部分体检人群EB病毒壳抗原免疫球蛋白A抗体(EBVCA-Ig A)和早期抗原免疫球蛋白A抗体(EA-Ig A)的阳性率和鼻咽癌的发病率。方法对2013年在长海医院进行EBVCA-Ig A抗体和EBEA-Ig A抗体检测的健康体检人群的结果进行统计分析。结果 14 032名健康人群中EBVCA-Ig A抗体阳性175人,阳性率为1.25%,EBEAIg A抗体阳性125人,阳性率为0.89%,共同阳性者5人,发现鼻咽癌1人,人群检出率约为7.13/10万。EBVCA-Ig A和EA-Ig A抗体的阳性率与年龄无相关性。结论在上海开展EBVCA-Ig A和EA-Ig A抗体的联合检测进行鼻咽癌的早期筛查具有一定的临床意义。

Objective To know the incidence of EBVCA-Ig A and EA-Ig A antibody and nasopharyngeal carcinoma（ NPC） among part of health population of Shanghai. Methods The results of EBVCA-Ig A and EA-Ig A antibody among part of health population from Shanghai Changhai Hospital in 2003 were statistically analyzed.Results In a total of 14 032 subjects 175 were EBVCA-Ig A antibody positive（ 1. 25%） and 125 were EA-Ig A antibody positive（ 0. 89%）. One NPC was found in 5 jointly positive cases of EBVCA-Ig A and EA-Ig A antibody and the prevalence of NPC was 7. 13 / 105. No association was calculated between antibody positive rate and age. Conclusion The joint detection of EBVCA- Ig A and EA- Ig A antibody has a certain clinical significance in aiding diagnosis of NPC in Shanghai.