正畸牙周联合治疗对中重度牙周炎患者骨钙素水平的影响

Influence of orthodontic periodontal combination therapy on osteocalcin level in patients with moderate-severe periodontitis

目的探讨正畸牙周联合治疗对中重度牙周炎患者骨钙素水平的影响及临床意义。方法选择2011年6月至2014年6月30例中重度牙周炎患者为观察组,选择同期牙周健康的需作正畸治疗患者30例为对照组。统计菌斑指数(PLI)、龈沟出血指数(BI)、牙周袋探诊深度(PD)及骨钙素水平。结果牙周治疗前观察组PD、BI、PLI均高于对照组(P<0.01);观察组正畸治疗前及正畸治疗后1、2个月PD、BI、PLI均较牙周治疗前降低(P<0.05);观察组不同时间点骨钙素水平均高于对照组(P<0.01),观察组加力后1d骨钙素水平达峰值,以后开始回落。结论正畸牙周联合治疗可以有效改善中重度牙周炎患者的牙周状况,检测患者龈沟液中的骨钙素水平可能反映出牙周炎患者的牙周炎症反应及牙槽骨改建过程。

Objective To study the influence of the orthodontic periodontal combination therapy on and clinical significance and its clinical significance.Methods 30 patients with moderate-severe periodontitis from June 2011 to June 2014 were selected as the observation group.Contemporaneous 30 patients with healthy periodontal tissue were selected as the control control.The plaque index（PLI）,gingival sulcus bleeding index（BI）and periodontal pocket agent diagnosis depth（PD）and osteocalcin levels in the two groups were tested.Results PD,BI,PLI before periodontal treatment in the observation group were higher than those in the control group（P〈0.01）;PD,BI and PLI before orthodontic treatment and in 1h,2months after orthodontic treatment in the observation group were reduced compared with before periodontal treatment（P〈0.05）;the osteocalcin levels at different time points in the observation group were higher than those in the control group（P〈0.01）,the osteocalcin level on 1dafter exerting stress in the observation group reached the peak,and then began to fall.Conclusion The orthodontic periodontal combination therapy can effectively improve the periodontal status in the patients with moderate-severe periodontitis,and detecting the osteocalcin level in gingiva groove liquid can reflect the periodontal inflammation reaction degree and alveolar bone reconstruction process in the patients with periodontitis.