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国产地西他滨联合CAG方案治疗高危骨髓增生异常综合征的疗效 被引量:6

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摘要 骨髓增生异常综合征(MDS)是一组异质性疾病,该病是起源于造血/祖细胞的异质性克隆性疾病,特征表现为病态造血,难治性血细胞减少,高风险向急性白血病转化[1-2]。中、高危型MDS患者,预后相对较差,可能与DNA异常甲基化导致抑癌基因失活有关,提示抑制DNA去甲基化为一个新的治疗靶点。随着表观遗传学[3-5]的深入研究。
出处 《实用临床医药杂志》 CAS 2016年第1期151-152,共2页 Journal of Clinical Medicine in Practice
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参考文献16

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