2011—2013年贵州省肿瘤医院常见多重耐药菌分析

Multidrug-resistant organisms in Guizhou Cancer Hospital in 2011-2013

目的了解某肿瘤医院多重耐药菌(MDRO)的分布情况,为医院感染防控提供依据。方法回顾性分析贵州省肿瘤医院2011—2013年临床送检标本中分离的MDRO监测资料。结果 2011—2013年共检出1 165株MDRO,产超广谱β-内酰胺酶(ESBLs)大肠埃希菌检出最多(626株,占53.73%),其次为耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)(209株,占17.94%);各年检出MDRO数量呈递增趋势。MDRO标本来源以痰/咽拭子(346株,占29.70%)、分泌物(322株,27.64%)及尿(227株,19.48%)为主;检出科室主要为重症监护病房(ICU)(210株,占18.03%),其次为泌尿外科(173株,占14.85%)。结论该肿瘤医院患者分离的MDRO主要来源于呼吸道、伤口分泌物及泌尿系统,应加强对高危科室及易感人群的监控,制定有针对性预防控制措施,遏制MDRO的感染和传播。

Objective To understand the distribution of multidrug-resistant organisms（MDROs）in a cancer hospital,and provide basis for the prevention and control of healthcare-associated infection（HAI）.Methods Monitored data of MDROs from clinical specimens in Guizhou Cancer Hospital in 2011-2013 were analyzed retrospectively.Results A total of 1 165 MDRO strains were isolated in2011-2013,most of which were extended-spectrum beta-lactamase-producing Escherichia coli（n=626,53.73%）,followed by methicillin-resistant coagulase negative staphylococcus（MRCNS,n= 209,17.94%）;MDRO detection rate increased year by year.MDROs were mainly isolated from sputum/throat swabs（n=346,29.70%）,secretion（n=322,27.64%）,and urine（n=227,19.48%）;intensive care unit and department of urology were the major departments of emergence of MDROs,accounting for18.03%（n=210）and14.85%（n=173）respectively.Conclusion MDROs in this hospital are mainly isolated from respiratory tract,surgical wound,and urinary system,monitoring of high-risk departments and susceptible population should be strengthened,targeted prevention and control measures should be developed to curb the infection and spread of MDROs.