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血清IL-6、BNP水平及RDW与慢性心力衰竭的相关性分析 被引量:5

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摘要 目的:探讨白细胞介素6(IL-6)、B型钠尿肽(BNP)水平及红细胞分布宽度(RDW)、与慢性心力衰竭(CHF)的相关性。方法:回顾性分析2012年1月-2015年2月的CHF患者210例,对照组选取100例健康体检者。CHF组参照纽约心功能分级(NYHA)分3组:Ⅱ级86例,Ⅲ级69例,Ⅳ级55例。同时,检测两组血清IL-6、BNP水平及RDW,分析与CHF的相关性。结果:CHF患者血清IL-6、BNP水平及RDW明显高于健康对照组(t=-38.919,-58.445,-17.619,P〈0.001)。CHF患者血清IL-6、BNP水平及RDW随着心功能的降低而升高,且各组间的差异有统计学意义(F=306.171,477.753,115.241,P〈0.001)。经Pearson相关分析证实血清IL-6、BNP水平及RDW与心功能分级呈显著正相关(r=0.673,0.735,0.592,P〈0.001)。结论:慢性心力衰竭患者血清IL-6、BNP及RDW高于健康对照组,且表达水平与CHF患者心功能分级正相关,是反映心功能有效的指标。
出处 《医疗装备》 2016年第2期37-38,共2页 Medical Equipment
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