阿维A联合潘生丁、西咪替丁治疗扁平疣的临床疗效观察

The clinical efficacy of Acitretin combined with Dipyridamole and Cimetidine in the treatment of flat wart

目的观察阿维A联合潘生丁、西咪替丁治疗扁平疣的临床疗效及不良发应。方法选择2013年1月-2015年3月收治的扁平疣患者120例,随机分为观察组和对照组各60例,观察组予阿维A联合潘生丁、西咪替丁治疗;对照组予潘生丁口服及阿昔洛韦乳膏外用,观察、比较2组治疗效果及不良发应。结果观察组总有效率为96.67%明显高于对照组的73.33%,差异有统计学意义(P<0.05)。观察组总不良反应率为13.33%明显低于对照组的30.00%;差异有统计学意义(P<0.05)。结论阿维A联合潘生丁及西咪替丁治疗扁平疣,临床疗效明显,值得临床推广应用。

Objective To observe the clinical efficacy and adverse response of acitretin combined with dipyridamole and cimetidine in the treatment of flat wart. Methods 120 cases of flat wart patients were selected in hospital from January2013 to March 2015,they were randomly divided into the observation group and control group. The observation group was treated with acitretin combined with dipyridamole and cimetidine treatment; control group received dipyridamole and acyclovir treatment. Observe and compare the therapeutic effects and adverse effects of the 2 groups. Results The total efficiency of observation group was 96. 67% significantly higher than the control group 73. 33%,the difference was statistically significant（ P 〈0. 05）. The observation group the total adverse reaction rate of 13. 33% was significantly lower than the control group30. 00%; the difference was statistically significant（ P 〈 0. 05）. Conclusion The clinical efficacy of acitretin combined with dipyridamole and cimetidine in the treatment of flat wart is significant,it is worthy of clinical application.