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Regioselective synthesis of α-bromo-α,β-unsaturated carbonyl compounds via photocatalytic α-bromination reactions

Regioselective synthesis of α-bromo-α,β-unsaturated carbonyl compounds via photocatalytic α-bromination reactions
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摘要 A visible light-mediated approach for the preparation of α-bromo-α,β-unsaturated ketones and aldehydes was developed. In comparison to traditional methods that generally take two steps to afford the above compounds, this protocol was highlighted by its operational simplicity, avoiding using hazardous bromine and mild reaction conditions. A visible light-mediated approach for the preparation of α-bromo-α,β-unsaturated ketones and aldehydes was developed. In comparison to traditional methods that generally take two steps to afford the above compounds, this protocol was highlighted by its operational simplicity, avoiding using hazardous bromine and mild reaction conditions.
出处 《Science China Chemistry》 SCIE EI CAS CSCD 2016年第2期190-194,共5页 中国科学(化学英文版)
基金 supported by the National Natural Science Foundation of China(21002018 21072038 21472030 21302029) the State Key Laboratory of Urban Water Resource and Environment(2015DX01) the Fundamental Research Funds for the Central Universities(HIT.BRETIV.201310)
关键词 visible light α-bromination α β-unsaturated ketones and aldehydes operational simplicity α-溴化反应 羰基化合物 不饱和醛 区域选择性合成 光催化 反应条件 可见光
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