新生儿高胆红素血症持续光疗和间断光疗的对照研究

Control Study of Phototherapy on Neonatal Hyperbilirubinemia Sustained and Intermittent

目的探讨给予高胆红素血症新生儿持续光疗和间断光疗的临床疗效及安全性。方法以2014年3月~2015年5月我院收治的140例高胆红素血症新生儿为研究对象,随机将入选患儿均分成两组。给予实验组患儿间断蓝光治疗,给予对照组患儿持续蓝光治疗,对比两组临床疗效及不良反应发生情况。结果 （1）实验组、对照组治疗后血总胆红素和经皮胆红素下降水平组间差异对比无统计学意义（P〉0.05）;（2）实验组不良反应发生率12.86%（9/70）,对照组不良反应发生率22.86%（16/70）,P〈0.05;（3）对照组患儿哭闹更为严重,影响护理人员日常工作。结论持续光疗和间断光疗均能有效改善新生儿高胆红素血症病状,但后者的不良反应及新生儿哭闹情况均少于前者,有利于治疗顺利开展。

Objective To investigate the clinical efficacy and safety of giving blood bilirubin in neonates with persistent phototherapy and intermittent photo the rapy. Methods 140 cases of neonatal hyperbilirubinemia from March 2014 to May 2015 in our hospital were taken as the research object and randomly divided into two groups. The experimental group of children were treated with intermittent blue light treatment, the control group of patients were treated with continuous blue light treatment, compared the clinical efficacy and adverse reactions of the two groups. Results（1） There was no significant difference between the experimental group and the control group（P〈0. 05）.（2） The incidence of adverse reactions in the experimental group was 12.86%（9/70）, the incidence of adverse reactions in the control group was 22.86%（16/70）, P〈0. 05.（3） The control group of children crying even more serious, affecting the daily work of nurses. Conclusion Modes of phototherapy and can effectively improve the symptoms of neonatal hyperbilirubinemia, but the adverse reactions and the newborn crying are less than the former, is conducive to the smooth development of treatment.