海南医学院附属医院2005—2009年肺癌患者诊治情况调查

A retrospective survey on diagnosis and treatment of the patients with lung cancer in the affiliated hospital of Halnan Medical College and its revelation

目的调查2005-2009年海南医学院附属医院住院肺癌患者的诊断与治疗情况。方法回顾性分析2005年1月1日至2009年12月31日201例住院肺癌患者的临床资料。结果201例肺癌患者平均发病年龄66岁，男女患者发病年龄差异无统计学意义。男性145例（72．1％），女性56例（27．9％），男女性别比2．6：1。男性肺癌患者中102例（70．3％）有吸烟史。临床诊断146例（72．6％），组织病理学诊断55例（27．4％）。无手术指征134例（66．7％），有手术指征67例（33．3％）；有手术指征中接受手术治疗17例（25．4％），不接受手术治疗50例（74．6％）。无化疗指征34例（16．9％），有化疗指征167例（83．1％）；有化疗指征中不接受化疗127例（76．0％），接受化疗40例（24．0％）；接受化疗者中完成4～6周期化疗的14例（35．0％），未完成的26例（65．0％）。接受放疗8例（4．0％）。靶向治疗3例（1．5％）。转院3例（1．5％）。结论该院住院肺癌患者构成比男性高于女性，男性发病与吸烟密切相关。肺癌患者主要依据胸部影像学进行临床诊断，组织病理学诊断率低，干预率低，放弃治疗率高。

Objective To investigate the diagnosis and treatment of the patients with lung cancer hospitalized in affiliated hospital of Hainan Medical College. Methods A retrospective study was performed from January 1 st 2005 to December 31th 2009 in the Hospital. 201 patients were enrolled in this study. Results The average onset age of patients with lung cancer was 66 years old. No difference in different gender. The incidence of male was 72.1% , which was ＇higher than of female（27.9% ）. Male to female ratio was 2~ 6 ： 1.70.3% of male patients with lung cancer had a history of smoking. 146 cases （72.6%） were diagnosed by clinical data, only 55 cases （27.4%） were diagnosed by histopathology. 134 cases（66.7% ） hadn＇t indications for surgery, only 17 cases（25.4% ） agreed to have surgery among 67 cases （33.3%） with indications for surgery,50 cases （74.5%） didn＇t agree to have surgery. 34 cases （16. 9% ） had no indications for chemotherapy. 40 cases （ 24. 0% ） agreed to have chemotherapy among 167 cases （83.1% ） with indications for chemotherapy, but only 14 cases （ 35.0% ） had completed 4 to 6 cycles of chemotherapy, and 26 cases（65.0% ） hadnt completed 4 to 6 cycles. 8 cases（4.0% ） agreed to have radiotherapy. 3 cases（ 1.5% ） agreed to have targeted therapy. 3 cases （ 1.5% ） transfered to other hospital. Conclusion The ratio of lung cancer patients in male is higher than female in the hospital, smoking is closely related to male patients. Clinical diagnosis rate of patients is high, whereas histopathologic diagnosis rate is low. The rate of the intervention that patients accepted is low and many patients give up available management after the diagnosis is made.