820例妇科门诊阴道分泌物临床检验分析

Analysis of Clinical Examination of Vaginal Secretion in 820 Cases From Gynecological Clinic

目的通过对妇科门诊育龄妇女阴道分泌物中病原微生物的检测,了解其阴道病原菌感染状况。方法采用阴道分泌物测定技术对820例妇科门诊就诊患者的阴道分泌物进行检测。结果 820例阴道分泌物细菌性阴道病(BV)感染率为13.29%(109/820),假丝酵母菌感染率为8.17%(67/820),滴虫感染率为1.10%(9/820),3组感染率比较差异有统计学意义(P<0.05);且BV合并假丝酵母菌感染6例,占0.73%;滴虫合并BV感染5例,占0.61%;820例阴道分泌物标本中,阴道清洁度I~Ⅱ度463例,占56.46%;清洁度Ⅲ~Ⅳ度357例,占43.54%;I^IV清洁度中,Ⅲ度和IV度人数相对较多,致病菌检出率也较I度和II度高。其中,III-IV度BV、假丝酵母菌、滴虫检出率明显高于I~Ⅱ度检出率,结果比较差异有统计学意义(P<0.05)。结论细菌性阴道病和假丝酵母菌是妇产科门诊生殖道感染的主要病原体,针对不同人群应做好相应的防护措施,促使其养成良好的卫生习惯,推动、普及育龄妇女阴道分泌物检查,以避免生殖道感染的发生。

Objective To detect the pathogenic microorganisms in vaginal secretion from women of childbearing age,and to explore the vaginal pathogens infection status. Methods The vaginal secretions of 820 women selected from Gynecology Outpatient Department were determined. Results Among the detected 820 women,the infection rate of bacterial vaginosis,Candida mycoderma bacteria and Trichomonas was 13. 29%（ 109 /820）,8. 17%（ 67 /820） and 1. 10%（ 9 /820）,respectively. The infection rate showed statistically significant difference among three groups（ P 〈0. 05）. Six cases were infected with bacterial vaginosis and Candida mycoderma bacteria,accounting for 0. 73%; five cases were infected by Trichomonas and bacterial vaginosis,accounting for 0. 61%. Among the detected 820 cases,the cleanness degree of vagina was I- II in 463 cases（ 56. 46%） and was III- IV in 357 cases（ 43. 54%）. The majority of detected cases were classified as III and IV cleanness degrees,and they had a higher infection rate of pathogenic bacteria than I and II degrees. Furthermore,the infection rate of bacterial vaginosis,Candida mycoderma bacteria and Trichomonas among III- IV degrees was significantly higher than that of I- II degrees,with statistically significant difference（ P 〈0. 05）.Conclusions Bacterial vaginosis and Candida mycoderma bacteria are the major pathogens of reproductive tract infection detected in the outpatients of Obstetrics and Gynecology Department. It is necessary to give different protective measures for different groups of population,develop good health habits,promote and popularize vaginal secretion examination among women of childbearing age,and accordingly avoid the infection of reproductive tract.