艾灸改善外周动脉疾病下肢经皮氧分压及运动功能的临床研究

Moxibustion Improved Transcutaneous Oxygen Tension and Exercise Capacity in Lower Limbs of Peripheral Arterial Disease

目的观察艾灸及平板运动对外周动脉疾病下肢经皮氧分压及运动功能的影响。方法将58例轻、中度外周动脉疾病患者按随机数字表法分为对照组(18例)、艾灸组(20例)和平板运动组(20例)。对照组患者只接受常规药物治疗,艾灸组在常规治疗的基础上予艾条灸足三里、三阴交及涌泉穴治疗,平板运动组在常规基础上予平板运动治疗;艾灸组和平板运动组患者均为每天1次,每周5次,共12周。观察各组治疗前后踝肱指数(Ankle-Brachial Index,ABI)、小腿经皮氧分压(transcutaneous oxygen tension,TcPO_2)、6分钟步行试验(6-min walking test,6MWT)及行走受损问卷(walking impairment questionnaire,WIQ)的评估结果。结果分别与本组治疗前及对照组比较,治疗后艾灸组及平板运动组ABI差异无统计学意义(P>0.05),TcPO_2、6MWT及WIQ值均明显提高(P<0.01),且平板运动组患者6MWT及WIQ评估均优于艾灸组(P<0.01)。结论艾灸及平板运动均可以改善外周动脉疾病患者下肢经皮氧分压及运动能力。

Objective To observe the effects of moxibustion and treadmill exercise on transcutaneous oxygen tension and exercise capacity in lower limbs of peripheral arterial disease（PAD）.Methods Totally 58 mild-to-moderate PAD patients were assigned to the control group（18 cases）,the moxibustion group（20 cases）,and the treadmill exercise group（20 cases） by random digit table.Patients in the control group received conventional drug therapy for 12 weeks.Patients in the moxibustion group and the treadmill exercise group additionally received moxibustion[at Zusanli（ST36）,Sanyinjiao（SP6）,Yongquan（KI1）]and treadmill exercise respectively,once per day,5 times per week for 12 weeks in total.Ankle-Brachial Index（ABI）,transcutaneous oxygen tension（TcPO2）,6-min walking test（6MWT）,and walking impairment questionnaire（WIQ） were assessed before and after treatment.Results Compared with the control group and the same group before treatment,there was no statistical difference in ABI in the moxibustion group and the treadmill exercise group（P 〉0.05）.But TcPO2,6MWT,and WIQ were obviously elevated（P 〈0.01）.Besides,6MWT and WIQ assessment of the treadmill exercise group were better than that of the moxibustion group（P 〈0.01） after intervention.Conclusion Moxibustion and treadmill exercise could improve the exercise capacity and TcPQ2of lower limbers in PAD patients.