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β-葡聚糖对创面愈合过程中细胞作用的研究进展 被引量:3

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摘要 β-葡聚糖是一种由β-糖苷键连接D-葡萄糖单体组成的多糖,其来源丰富、结构多样,具有多种生理功能。目前对其降血脂、降血糖、抗肿瘤、抗感染、免疫调节等功能有很多报道,但对其促进创面愈合的作用尚无系统报道。本文通过查阅近年来国内外相关文献,对β-葡聚糖促进创面愈合的作用进行总结。文献分析表明,β-葡聚糖能够刺激巨噬细胞、成纤维细胞、角化细胞以及淋巴细胞等重要细胞,使其活化、增殖、迁移,并释放多种细胞因子,从而增强细胞功能,有助于抗炎抑菌、胶原合成、肉芽组织生长、创面再上皮化及创面愈合后的改建,从而促进创面的愈合。本文主要阐述了β-葡聚糖对创面愈合过程各类细胞的作用并系统地总结其对整个创面愈合过程的影响,为揭示其促进创面愈合的细胞学机制提供了理论基础和依据。
出处 《中国预防医学杂志》 CAS 2016年第1期64-68,共5页 Chinese Preventive Medicine
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参考文献48

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