支气管肺炎患儿血小板计数变化及临床意义

The clinical significance of changes of platelet count in children with bronchial pneumonia

目的：探讨支气管肺炎患儿血小板计数变化及在病情中的临床意义。方法对收治的320例支气管肺炎患儿进行回顾性分析，根据入院后的血小板计数，分为血小板增多组（＞400×109／L）和血小板正常组（100～400×109／L），对两组患儿的年龄、性别、呼吸困难发生率、治疗时间、白细胞计数、血红蛋白、CRP等临床资料进行统计分析。结果320例患儿中血小板增多62例，血小板正常258例。与血小板正常组比较，血小板增多组患儿年龄更小（年龄＜1岁为主占46．77％，前者1～3岁为主占40．70％，Z ＝2．08）、治疗时间延长[（7．37±1．90）d，前者为（6．79±1．51）d，t ＝2．56]、血白细胞计数增高[（10．71±3．91）×109／L，前者为（9．37±3．56）×109／L，t ＝2．61]，以上差异均有统计学意义（均 P ＜0．05）；呼吸困难发生率更高（占74．19％，前者占52．33％，χ2＝9．73）、血红蛋白降低[（104±14）g／L，前者为（111±13）g／L，t ＝3．34]、CRP 增高[（24．42±12．73）mg／L，前者为（18．31±8．86）mg／L，t ＝3．58]，以上差异均有统计学意义（均 P ＜0．01）。两组在性别上差异无统计学意义。结论支气管肺炎患儿发生血小板增多者年龄更小，病情更重。观察血小板计数变化有助于患儿病情的正确判断及有效治疗。

Objective To explore the changes of platelet count in children with bronchial pneumonia and its clinical significance in the disease.Methods 320 cases of bronchial pneumonia were retrospectively analyzed after hospitalization.According to the number of platelet count,the cases were divided into increased platelet count group （〉400 ×109 /L）and normal platelet group（100 -400 ×109 /L）,and the clinical data of two groups were statistically analyzed,such as age,gender,dyspnea,treatment,white blood cell count,hemoglobin,C -reactive protein.Results In 320 cases,62 cases＇;platelet count increased,258 cases were normal.Compared with the normal platelet group,the cases in increased platelet count group had the following characteristics：younger（〈1 year old mainly,accounted for 46.77%;the former was between 1 and 3 years old mainly,accounted for 40.70%;Z =2.08）,treatment time pro-longed （7.37 ±1.90）d,the former was （6.79 ±1.51）d,white blood cell count increased [（10.71 ±3.91）×109 /L,the former was （9.37 ±3.56）×109 /L,t =2.61,P 〈0.05];the incidence rate of dyspnea was higher （74.19%, the former was 52.33%,χ2 =9.73）,hemoglobin decreased [（104 ±14）g/L,the former was （111 ±13）g/L,t =3.34],C -reactive protein increased [（24.42 ±12.73）mg/L,the former was （18.31 ±8.86）mg/L,t =3.58,P 〈0.01].There was no significant difference in gender between the two groups.Conclusion Children with bronchial pneumonia who platelet count increased are younger and their diseases are more serious.Observation the platelet count change can help to rightly judge and effective treat.