同型半胱氨酸在原发性高血压患者中的检测意义

Study on detection significance of homocysteine in patients with essential hypertension

目的研究同型半胱氨酸在原发性高血压中的检测意义,为今后原发性高血压疗效提升及疗效判定提供参考。方法将132例原发性高血压患者按治疗方法不同随机分成对照组和研究组,根据血压级别将所有患者进行划分,观察治疗前三个级别患者同型半胱氨酸水平及治疗前后同型半胱氨酸水平。结果血压级别越高,血浆同型半胱氨酸水平越高,3级患者最高,且3级中高Hcy血症比重(100.00)最高;治疗后,两组患者血浆同型半胱氨酸水平均明显下降,研究组患者同型半胱氨酸水平较对照组低。P均<0.05。结论同型半胱氨酸可作为原发性高血压病情评估指标,可用于疗效评估,指导治疗。

Objective To study the significance of homocysteine in the detection of essential hypertension,and to provide reference for the improvement of the efficacy and the efficacy of the treatment of essential hypertension in the future. Methods 132 patients with essential hypertension were randomly divided into control group and study group. All patients were divided into three groups according to blood pressure level,and the level of homocysteine in the first 3 levels of the treatment group were observed before and after treatment.Results The higher the level of blood pressure,the higher plasma homocysteine levels,and level 3 is the highest,and level 3 high proportion of Hcy levels,highest（ 100. 00）; After treatment,All patient ＇s plasma homocysteine levels were significantly decreased,the homocysteine levels of patients in the study group was lower than the control group,There was statistical significance,P〈 0. 05. Conclusions Homocysteine can be used as an evaluation index of essential hypertension,which can be used for the evaluation of therapeutic effect.