噻托溴铵＋普米克令舒＋万托林三联用药治疗老年慢性阻塞性肺气肿加重期疗效及安全性评价

Efficacy and safety evaluation of Tiotropium + Pulmicort + Ventolin 3 drug treatment of increased senile chronic obstructive emphysema

目的探究噻托溴铵+普米克令舒+万托林三联用药治疗老年慢性阻塞性肺气肿加重期疗效及安全性评价。方法将我院收治的100例老年慢性阻塞性肺气肿患者随机分成两组,对照组和实验组。对照组的治疗方案是生理盐水+普米克令舒+万托林雾化治疗;实验组的治疗方案是生理盐水+普米克令舒+万托林+噻托溴铵气雾剂吸入治疗,观察并对比两组患者的治疗效果,进行安全性评价。结果对照组治疗的总有效率是82%,实验组治疗的总有效率是92%;对于两组患者治疗后的治疗后肺功能比较(包括FEV1值占预计值百分比和FEV1/FVC),实验组的治疗后效果强于对照组;对于治疗前后血气分析结果比较情况,两组患者治疗后均有所进步,实验组进步更加明显;对于两组患者的症状体征平均消失时间及住院天数,实验组短于对照组。结论对于老年慢性阻塞性肺气肿加重期的治疗,采用噻托溴铵+普米克令舒+万托林三联用药进行治疗的疗效显著,可以广泛推广。

Objective To investigate the Sai tiotropium bromide ＋ Pulmicort Respules ＋ Ventolin 3 combination treatment of elderly chronic obstructive emphysema increased efficacy and safety evaluation.Methods 100 cases of elderly patients with chronic obstructive pulmonary emphysema were randomly divided into two groups,the control group and the experimental group. Control group in the treatment of saline ＋ Pulmicort order ＋ Shu Ventolin treatment; treatment of experimental group is saline ＋ Pulmicort order ＋ Shu Ventolin ＋hydrochlorothiazide supporting bromide aerosol inhalation treatment,observed and compared between the two groups of patients treatment effect and safety evaluation. Results The total effective rate of the control group was 82%,and the total effective rate was 92%. For the two groups of patients after treatment,the effect was stronger than that of the control group. After treatment,two groups of patients were improved. The symptoms and signs of the two groups were more obvious. Conclusions For the treatment of senile chronic obstructive emphysema exacerbation,the Sai tiotropium bromide ＋ Pulmicort Respules ＋ Ventolin 3 combination of curative effect significantly,can be widely applied.