二代测序技术在成熟淋巴肿瘤研究中的应用进展：第57届美国血液学会年会报道

Application of next generation sequencing in the study of mature lymphoid malignancies： reports from the 57th American Society of Hematology annual meeting

二代测序技术近年来逐渐开始应用于成熟淋巴肿瘤的科学研究和临床实践。第57届美国血液学会（ASH）年会报道了多项二代测序技术在淋巴肿瘤发病机制研究、临床治疗、预后评估和耐药机制研究中的应用。文章选取有代表性的报道，总结二代测序技术在成熟淋巴肿瘤研究中的应用进展。

Next generation sequencing （NGS） has been applied in scientific research and clinical practice of mature lymphoid malignancies. The applications of NGS in the study of pathogenesis, treatment and prognosis evaluation, mechanisms of resistance to treatment in lymphoid malignancies have been reported in the 57th American Society of Hematology （ASH） annual meeting. This article summarized the advances in the use of NGS in mature lymphoid malignancies by reviewing several representative reports.