摘要
人体健康与肠道菌群息息相关,越来越多的研究显示正常菌群不仅在消化、免疫等方面有诸多不可替代的作用,肠道菌群结构的改变与失衡更是与肥胖、糖尿病、心脑血管疾病、肿瘤等多种疾病密切相关。最新研究表明药物刺激免疫系统引起的抗肿瘤免疫反应以及自身免疫反应都离不开肠道菌群的参与,肠道菌群能够通过调节免疫反应增强肿瘤治疗效果。
Human health is related to intestinal flora closely,more and more studies showed that the normal flora played an important role in terms of digestion,immunity,obesity,diabetes,cardiovascular disease,cancer and many other diseases. Recent studies showed that chemotherapy drugs stimulated antitumor immune responses and autoimmune responses required the participation of intestinal flora. The intestinal microbiota could affect the therapeutic effects by modulating the immune responses effects.
出处
《工业微生物》
CAS
CSCD
2016年第1期53-56,共4页
Industrial Microbiology
基金
国家"重大新药创制"科技重大专项(No.2013ZX09301302
No.2014ZX09507009-025)
国家自然科学基金(No.81573329)
关键词
肠道菌群
人体健康
免疫反应
肿瘤治疗
intestinal microbiota
human health
immune responses
oncotherapy