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放射性肺纤维化的分子机制及其防治药物综述 被引量：9

Review on molecular mechanisms and protective drugs research on radiation-induced lung fibrosis
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摘要 对放射性肺纤维化(Radiation-induced lung fibrosis,RILF)的发生、发展和最终形成过程中涉及到的细胞、细胞因子、信号通路以及关键因子进行归纳、总结和讨论,并给出具有潜在治疗作用的靶点以及作用在该靶点的相关药物,为今后研发预防与治疗RILF的药物提供思路。 The current understanding of the cells, cytokines, and the key factors linked to the signaling networks implicated in RILF were summarized. Targets with potential therapeutic effects for the treatment of RILF were also be discussed and listed. From all above, we hope to provide researchers with ideas in studying the drugs with prevention and （or） the treatment of RILF.
作者 郑啓盛 刘培勋
机构地区 北京协和医学院&中国医学科学院放射医学研究所天津市放射医学与分子核医学重点实验室
出处 《辐射研究与辐射工艺学报》 CAS CSCD 2016年第1期1-10,共10页 Journal of Radiation Research and Radiation Processing
基金 北京协和医学院协和青年创新基金(1568) 中国医学科学院放射医学研究所探索基金(1560)资助~~
关键词 放射性肺纤维化 分子机制 细胞因子 防护药物 综述 Radiation-induced lung fibrosis（RILF）, Molecular mechanisms, Cytokines, Protective drugs, Review
分类号 R979.6 [医药卫生—药品] R818 [医药卫生—放射医学]
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参考文献52

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二级参考文献43

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辐射研究与辐射工艺学报
2016年 第1期

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