摘要
采用宽带激光熔覆技术,通过在涂层中加入稀土氧化物Nd_2O_3来改善涂层显微组织、表面形貌和提高涂层生物活性、细胞相容性的方法,制备了一种梯度生物活性陶瓷涂层。利用金相分析、SEM分析手段对涂层显微组织、形貌进行了研究;通过模拟体液(SBF)浸泡实验考察了涂层活性;采用人成骨细胞与涂层材料共培养的方式,验证了细胞在涂层表面的粘附生长和定向分化能力。结果表明:涂层中添加Nd_2O_3时,涂层显微组织和表面形貌优于没有加入Nd_2O_3的涂层;加入Nd_2O_3的涂层表面生成的HA+β-TCP相多于没有添加Nd_2O_3的涂层,生物活性更好;添加Nd_2O_3的涂层具有更好的细胞相容性和细胞活性。
The rare earths active gradient bioceramic coating with HA and β-TCP on TC4 titanium alloy was prepared by using wide-band laser cladding technique and by adding rare earth oxide Nd2O3 to improve the coating microstructure,surface morphology and to improve the biological activity of the coating,compatibility of the cells.The coating microstructure,morphology was studied by optical and SEM analysis. The effects of immersion coating activity was simulated by body fluid( SBF),the human osteoblast verifies the adhesion and directed differentiation capacity of the cells grown in the coating surface. The results showed that adding Nd2O3,the microstructure and surface morphology of the coating is better than that without Nd2O3,added coating has better biocompatibility and cell viability.
出处
《中国稀土学报》
CAS
CSCD
北大核心
2016年第1期105-112,共8页
Journal of the Chinese Society of Rare Earths
基金
贵州省科技创新人才团队建设项目[科合人才团队(2010)4004]
贵州省优秀青年科技人才培养项目[黔科合人字(2015)04]资助