克罗恩病并发下消化道大出血的临床诊治进展

Diagnosis and treatment of Crohn's disease complicated by massive lower gastrointestinal hemorrhage

克罗恩病(Crohn's disease,CD)是一种病因不明的肠道慢性、肉芽肿性炎症.随着人们生活方式的改变及诊断方法的进步,确诊为CD的患者呈增多趋势.在疾病发展过程中,部分患者可出现肠梗阻、腹腔内脓肿、急性穿孔或消化道出血等并发症.下消化道大出血并非CD的常见并发症,其诊断存在一定难度,较其他原因所致下消化道大出血,CD并发下消化道大出血治疗上有其特点,本文将对CD并发下消化道大出血近年在诊断和治疗方面的进展作一综述.

Crohn＇s Disease （CD） is a chronic granulomatous inflammatory disorder of the gastrointestinal tract. With the change of the life style andthe progress of the diagnosis method, the number of patients diagnosed with CD has increased in China. In the course of disease development, some patients may have intestinal obstruction, abdominal abscess, acute perforation, gastrointestinal bleeding or other complications. Massive lower gastrointestinal hemorrhage is not a common complication of CD, and is a challenge for diagnosis and therapeutic management. It is more difficult to diagnose and treat CD associated lower digestive tract hemorrhage, compared with massive hemorrhage of lower digestive tract caused by other reasons. This paper reviews recent advances in the diagnosis and management of CD complicated with severe lower gastrointestinal hemorrhage.