磷酸西格列汀在2型糖尿病治疗中的应用研究

Efficacy of Sitagliptin Phosphate in Treatment of Type Ⅱ Diabetes

目的对磷酸西格列汀应用于2型糖尿病治疗中的效果进行分析研究。方法选取于2013年11月-2015年12月在我院收治的2型糖尿病患者116例,并随机分为对照组和治疗组各58例,观察并比较常规治疗和加用磷酸西格列汀的效果。结果治疗组患者的治疗总有效率高于对照组[93.1%vs 75.9%],治疗组患者的空腹血糖、餐后2 h血糖、糖化血红蛋白以及胰高血糖素水平均低于对照组,组间差异经t检验,有统计学意义（P〈0.05）。结论磷酸西格列汀应用于2型糖尿病治疗中的效果确切。

Objective Sitagliptin Phosphate effect in treatment of type II diabetes is to be analyzed. Methods chose 116 patients of type II diabetes who were treated in hospital from November 2013 to December 2015 and separated them into Control Group and Study Group randomly with 58 patients in each group, and then observed and compared conventional medication effect to Sitagliptin Phosphate treatment effect. Results The treatment efficacy in Study Group was also higher than that in Control Group [93.1% vs 75.9%]; while, patients＇ fasting blood glucose, postprandial 2 hours＇ blood glucose, glycosylated hemoglobin and glucagon level in Study Group were significantly lower than counterparts in Control Group; there was a difference between groups according to T-Check, and such a differential had statistic vale（P〈0.05）. Conclusion Sitagliptin Phosphate application is effective in treatment of type II diabetes, thus, such a medication treatment is quite worthwhile to be promoted widespread.