长效胰岛素联合口服降糖药治疗2型糖尿病的临床观察

Clinical Observation of Long-acting Insulin and Oral Hypoglycemic Agents in the Treatment of Type 2 Diabetes

目的观察长效胰岛素联合口服降糖药治疗2型糖尿病的临床疗效。方法收集2型糖尿病患者104例,随机分为观察组(长效胰岛素+口服降糖药)与对照组(单用长效胰岛素)。结果治疗前,两组FBG、2 h PBG及Hb Alc对比,无差异(P>0.05);治疗后,观察组FBG、2 h PBG及Hb Alc均优于对照组,差异具有统计学意义(P<0.05);两组低血糖发生率比较,差异具有统计学意义(P<0.05),结论长效胰岛素+口服降糖药治疗2型糖尿病疗效显著。

Objective To observe the clinical efficacy of long-acting insulin in type 2 diabetes combined with oral hypoglycemic agents. Methods 104 cases of type 2 diabetes were randomly divided into two groups（long-acting insulin and oral hypoglycemic agents）and control group（single long-acting insulin）. Results Before treatment,the two groups FBG,2 h PBG and Hb Alc contrast,no significant difference（P〈0.05）,after treatment,the observation group FBG,2 h PBG and Hb Alc were better than the control group,the difference was significant（P〈0.05）. View groups the incidence of hypoglycemia,the difference was significant（P〈0.05）. Conclusion The long-acting insulin and oral hypoglycemic agents to treat type 2 diabetes a significant effect.