阿莫西林克拉维酸钾联合糜蛋白酶治疗儿童急性化脓性扁桃体炎疗效观察

Efficacy of Amoxicillin-Clavulanate Potassium Combined With Chymotrypsin for Pediatric Acute Suppurative Tonsillitis

目的探讨阿莫西林克拉维酸钾联合糜蛋白酶治疗儿童急性化脓性扁桃体炎的疗效。方法选取我院100例化脓性扁桃体炎患儿,随机分为观察组和对照组,每组患者均为50例,对照组单用阿莫西林克拉维酸钾,观察组在此基础上加用糜蛋白酶治疗,比较两组治疗后主要症状体征改善时间、总有效率和不良反应。结果观察组症状改善时间优于对照组,总有效率高于对照组,差异均有统计学意义(P<0.05)。结论阿莫西林克拉维酸钾联合糜蛋白酶治疗儿童急性化脓性扁桃体炎,能缩短症状持续时间,提高治疗有效率。

Objective The research aims to explore the clinical effect of amoxicillin-clavulanate potassium combined with chymotrypsin on pediatric acute suppurative tonsillitis. Methods The research chose 100 cases of children patients with suppurative tonsillitis from the hospital,and distributed them into the observation group and the control group randomly of which each had 50 cases. The control group received the treatment of amoxicillinclavulanate potassium alone,while the observation group received the additional treatment of chymotrypsin on the basis. After the treatment,the research compared the two groups in terms of the improvement time of main symptoms and signs,total effective rate and untoward effect. Results The symptoms improve time of in the observation group were significantly better than that in the control group,the total efficiency in the observation group were significantly higher than that in the co Tntrol group（P〈0.05）. Conclusion Treating pediatric acute suppurative tonsillitis with amoxicillin-clavulanate potassium combined with chymotrypsin can reduce the duration of symptoms and improve the effective rate of treatment,thus should be spread and applied clinically.