帕瑞昔布钠用于术后镇痛对患者镇痛效果及对肝肾功能的影响分析

Effect of Postoperative Analgesia With Parry Sodium on Liver and Renal Function and Its Effect on Liver and Renal Function

目的研究帕瑞昔布钠用于术后镇痛对患者镇痛效果与肝肾功能的影响。方法挑选2012年1月-2015年3月在我院接受妇科手术的患者68例,随机分成两组,每组各有患者34例,其中一组患者在关腹后,给予40 mg帕瑞昔布钠静脉注射,连接PCEA泵,称为研究组,另一组患者在关腹后直接与PCEA泵连接,称为对照组,记录研究组患者及对照组患者在手术后的疼痛情况,并检测患者的肝肾功能,进行比较。结果研究组患者与对照组患者在肝肾功能方面无差异,不存在统计学意义（P〉0.05）;研究组患者的疼痛评分低于对照组患者,差异存在统计学意义（P〈0.05）。结论给予手术患者帕瑞昔布钠能有效缓解患者的疼痛程度,但不会对患者的肝肾功能有影响,安全性高。

To study effect of postoperative analgesia with parry sodium on liver and renal fimction and its effect on liver and renal function.Methods collcected in January 2012 to March 2015 in our hospitnl accepted gynecolocal surgery in 68 patients were nmdomlv divided into two grcoups. Each group had 34 cases of patients, which a group of patients after abdominal closure, giving 40 nag parecoxib sodium intravmmus injection, PCEA pump, known as the sttldy goup, another gmup of patients after abdominal closure in directly with the PCEA pump comection, known as the control gnoup, the patients m the study goup were recorded and control groups were compared in pain afi-er surgery, and the detection of patients with liver and kidney fimction. Resttls Patients in the study group and the control group no diffcrence m liver and kidney fimction, there is no statistical sibmificancc （P 〉 0.05 ）, pain scores of patients in the study group was lower than that in the control gncoup, the difference was statistically significant （ P 〈0.05 ） . Conclusion Given surgery patients with parecoxib sodium ca）） effecfively relieve the pare of pafients, but not in patients with liver and kidney function effect and high safety.