肾功能不全患者抗感染治疗用药思考被引量：9

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摘要肾脏是维持人体体液及电解质的重要脏器,肾功能不全患者的抗生素体内分布、药物清除率和排泄等药动学参数均可发生不同程度的改变,并可因此影响患者的肾功能。本文将重点讨论:1肾功能不全时抗菌药物的药代动力学变化;2肾功能不全患者抗菌药物选择的主要影响因素;3肾脏替代治疗时抗菌药物的应用。

作者佑航标张文平陈洋马利军

机构地区新乡医学院(河南省人民医院)

出处《中国现代药物应用》 2016年第5期283-285,共3页 Chinese Journal of Modern Drug Application

关键词肾功能不全抗生素药代动力学血液透析

分类号 R969 [医药卫生—药理学]

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