GSK3β、JNK对脑缺血再灌注后微血管生成机制的研究进展

Progress Research in GSK3β and JNK on Angiogenesis Mechanism after Cerebral Ischemic- reperfusion

GSK3β、JNK参与调节脑缺血再灌注后半暗带区微血管的生成，为缺血性脑血管疾病的临床治疗提供了新的思路。本文从GSK3β和JNK的结构、功能、活化及其与血管生成的关系等方面，就近年来有关GSK3β、JNK在脑缺血再灌注后微血管生成机制方面的研究进展做一综述。

GSK3β and JNK regulate angiogenesis of penumbra area after cerebral ischemic - reperfusion, and provide a new way for clinical treatment of ischemic cerebrovaseular disease. The article discusses the research progress in GSK3β and JNK on angiogene- sis mechanism after cerebral ischemic -reperfusion.