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Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders 被引量：3

Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders
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摘要 Direct reprogramming of somatic cells into neurons or neural stem cells is one of the most important frontier fields in current neuroscience research. Without undergoing the pluripotency stage, induced neurons or induced neural stem cells are a safer and timelier manner resource in comparison to those derived from induced pluripotent stem cells. In this prospective, we review the recent advances in generation of induced neurons and induced neural stem cells in vitro and in vivo and their potential treatments of neurological disorders. Direct reprogramming of somatic cells into neurons or neural stem cells is one of the most important frontier fields in current neuroscience research. Without undergoing the pluripotency stage, induced neurons or induced neural stem cells are a safer and timelier manner resource in comparison to those derived from induced pluripotent stem cells. In this prospective, we review the recent advances in generation of induced neurons and induced neural stem cells in vitro and in vivo and their potential treatments of neurological disorders.
作者 Shaoping Hou Paul Lu
机构地区 Spinal Cord Research Center Veterans Administration Medical Center Department of Neurosciences
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第1期28-31,共4页 中国神经再生研究（英文版）
基金 supported by the Veterans Administration the Craig H.Neilsen Foundation(280072 to SH) the California Institute for Regenerative Medicine
关键词 neural cells induced neural stem cells induced neurons pluripotent stem cells neurological diseases neural cells induced neural stem cells induced neurons pluripotent stem cells neurological diseases
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献29

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Neural Regeneration Research
2016年 第1期

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