摘要
The systemic health benefits of regular skeletal muscle activity are well documented.Increased skeletal muscle activity is associated with an improved systemic metabolic state,reduced incidence of diabetes and obesity,and improved function with age.Despite these known systemic benefits,many healthy people do not meet the recommended daily dose of skeletal muscle activity（exercise）needed to prevent systemic metabolic disease,leading to an in-creased prevalence of obesity.
The systemic health benefits of regular skeletal muscle activity are well documented.Increased skeletal muscle activity is associated with an improved systemic metabolic state,reduced incidence of diabetes and obesity,and improved function with age.Despite these known systemic benefits,many healthy people do not meet the recommended daily dose of skeletal muscle activity（exercise）needed to prevent systemic metabolic disease,leading to an in-creased prevalence of obesity.
基金
supported in part by awards from the National Institutes of Health–National Center for Medical Rehabilitation Research(R01HD084645
R01HD082109)
