加味通幽汤治疗老年性功能性便秘临床疗效观察

Clinical Observation on Jiaweitongyou Decoction in Treatment of Senile Functional Constipation

目的观察加味通幽汤治疗老年性功能性便秘的临床疗效。方法收集60例老年性功能性便秘的患者,随机分为治疗组与对照组,每组各30例。治疗组给予加味通幽汤治疗;对照组给予乳果糖口服。两组均治疗4周后,观察治疗前后的便秘主要症状积分、临床总体疗效及停药4周后便秘主要症状积分。结果治疗组总有效率优于对照组(P<0.05)。两组在便秘主要症状积分上比较,差异有统计学意义(P<0.05)。且治疗组在停药4周后与治疗前比较具有统计学意义(P<0.05);与对照组停药4周后比较,差异也有统计学意义(P<0.05)。结论加味通幽汤治疗老年性功能性便秘比口服乳果糖效果更佳,安全可行。且四周后对便秘主要症状积分的改善明显优于对照组。

Objective To observe the clinical effect of Jiaweitongyou decoction on senile functional constipation. Methods 60 patients with senile functional constipation were randomly divided into treatment group and control group,30 cases in each group. The treatment group received Jiaweitongyou decoction,the control group received Lactulose. After treatment of 4 weeks,compare the constipationmain clinical symptom score and the clinical curative effect before and after treatment,and the constipation main symptom score after stopping taking medication for 4 weeks. Results Four weeks after treatment,there was a significant difference（ P〈0. 05） between treatment group and control group in clinical curative effect after weak treatment of 4 weeks. Comparing the constipationmain clinical symptom score,there was a significant difference（ P〈0. 05） between treatment group and control group before and after treatment. There was a significant difference（ P〈0.05） compared with after stopping taking medication for 4 weeks. There was a significant difference（ P〈0. 05） between treatment group and control group in constipation main clinical symptom score after stopping taking medication for 4 weeks. Conclusion Jiaweitongyou decoction has a better clinical efficacy in treatment of senile functional constipation,it is safe and feasible. In addition,after stopping taking medication for 4 weeks,the improvement of constipation main clinical symptom scores were more significant than control group.